Advance stage prostate cancer: What are the signs and symptoms?

The most challenging part of the late stage prostate cancer is a lack of response to treatment. Late stage prostate cancer implies that patients have failed or have not tolerated common methods of treatments.

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Written By: Debjani Arora | Published : October 4, 2018 6:41 PM IST

The last stage prostate cancer is usually the advanced stage of the cancer this means that the cancer has metastasis and it doesn't response to treatment well. Metastasis refers to the spread of your prostate to other parts of the body through the blood stream or the lymphatic system. The lymphatic system produces antibodies that are essential to fight off infections. Prostate cancer mostly metastasizes to:

  • Adrenal gland
  • Bone
  • Liver
  • Lung

The most challenging part of the late stage prostate cancer is a lack of response to treatment. Late stage prostate cancer implies that patients have failed or have not tolerated common treatments. Prostate cancer is often without symptoms early on. Because of the popularity of the PSA test, many men are diagnosed early. However, as prostate cancer progresses, many men do experience symptoms. Sometimes a small percentage of men are initially diagnosed with late stage disease.

Many of the symptoms below can also overlap with other diseases of the prostate such as benign prostatic hypertrophy (BPH) or prostatitis. BPH is a noncancerous enlargement of the prostate which presses on the urethra (the tube that goes from the kidney to the end of the penis that your urine passes through) to cause symptoms. Prostatitis is an inflammatory condition, sometimes associated with a bacterial or viral infection, leading to prostate symptoms. However the most common late stage prostate cancer symptoms can include:

  • Weak urinary stream: Where the urine output is almost negligible despite having a full bladder.
  • Incomplete emptying and frequent starts and stops when urinating: This happens abruptly.
  • Hematuria or blood in the urine: This signifies danger.
  • More frequent urination: Since the bladder doesn't empty on time.
  • Dysuria or pain when urinating: Pain indicates that the cancer has reached its last stage.
  • Bone pain: If the cancer has metastases to the bones it can cause bone pain too.
  • Weight loss: Weak immunity and spread of the disease leads to low appetite and a sluggish digestion that lead to weight loss.
  • Fatigue: This is an obvious outcome of the cancer spread.
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