The term 'blister' is commonly associated with skin conditions and diseases. It comes from the word 'blostre' that means leprous nodule or vesicle in old French. Basically, blister is a vesicle with a diameter of 5 mm or more. The vesicle is usually filled with a clear fluid called serum. This fluid forms a part of the blood devoid of red blood cells and blood clotting agents. Sometimes, the blister can get filled with pus if the area gets infected with bacteria.
Skin blisters occur because of irritation of the skin caused due to external damage. Usually, a single blister may appear when something like a shoe rubs against the skin surface. It can also occur due to minor burn injuries or chemical allergens and may typically erupt on the hands and the feet. Multiple blisters on the skin can be an indication of a serious skin condition that needs attention. In children, multiple blisters are usually found in chicken pox.
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