Pedicures are one of the best ways to deal with corns or calluses. But not every time can you go for it (cost being a big factor). Though OTC medications available to treat them there are numerous side-effects associated with them as well. Instead go for a cheaper effective and at-home remedy to get rid of corns aspirin. How it helps Corns and calluses cause swelling and patches of hardened dead skin on the feet. The salicylic acid present in aspirin acts as an antiseptic and anti-inflammatory agent that in turn aid in treating the infection and also relieve swelling.