Genetic incompatibility may be the reason why many kidney transplants fail even when donors and recipients are thought to be well-matched a recent study has observed. According to the study published in the Journal of Medicine genomic collision is a genetic incompatibility between the kidney donor and recipient causing the recipient to mount an immune attack against the donor protein. The new study could lead to more precise matching between donors and patients and reduce kidney transplant failures. Also the same genomic collision may potentially occur in heart liver and lung transplants.A successful organ transplant depends on assuring genetic compatibility