Sign In
  • ENG

Diabetes affects your sperm too!

Written by Editorial Team |Updated : October 8, 2014 8:14 PM IST

sperm-dnaAccording to findings of a study by Jaslok Hospital and Research Centre in Mumbai, diabetes increases the risk of DNA damage in sperms, resulting in infertility. The on-going study which has found that DNA damage among diabetics is more than double as compared to those who are non-diabetics also showed that sperm count is significantly reduced and the movement and appearance of sperm is affected by diabetes. India is the diabetes capital of the world. Every fifth Indian is estimated to be a diabetic and it's alarming that increasing numbers of diabetics are seeking infertility treatments.

Diabetic men were nearly three times more likely to suffer from sperm apoptosis (break-up of the DNA) than non-diabetics. Higher miscarriage rates in couples may also be seen due to fragmented or broken DNA. 'It is known that diabetic men may take a longer time to bring about conception in their wives who may also be prone to a higher incidence of miscarriage,' said Dr Firuza Parikh, director, department of assisted reproduction and genetics, Jaslok Hospital.

The study, which was presented at a seminar on Male Infertility conducted by the centre last week, has found that in diabetes the DNA of the sperm is damaged due to oxidative stress which releases cell death accelerating ions in the body.

Also Read

More News

Read more about causes, symptoms, diagnosis and treatment of diabetes.

The sperm count, motility and morphology (sperm structure) of 60 diabetics and 78 non-diabetics in the age group of 25 to 45 years were studied by Dr Parikh and his team at the assisted reproduction and genetics department. According to Dr Prochi Madon, head, genetics lab at the centre, all these men were newly-diagnosed diabetics who had come to the clinic for infertility treatment. The study which was initiated three years ago found that DNA damage in the diabetic group was 15.9% as compared to 6.4% among the non-diabetic group. The study also found that in diabetics the sperm's motility was 22% as against 46% in healthy individuals. Also, the sperm count diabetic men was less than half of that of the healthy group. 92% of the diabetic men had abnormal sperm structure as opposed to 11% of the normal group.

According to Dr Arundhati Athalye and Dr Meenal Khandeparkar, the study underlined the need to perform routine DNA fragmentation testing in every diabetic patient seeking infertility treatment. There is a need to assess if antioxidants in tablet form can improve the sperm quality to reduce oxidative stress on the sperm, said Dr Arundhati Athalye, principal investigator of the study.

You may also like to read:

For more articles on diabetes, check out our diabetes section and Diabetes page. Follow us on Facebook and Twitter for all the latest updates! For daily free health tips, sign up for our newsletter. And to join discussions on health topics of your choice, visit our forum.

Total Wellness is now just a click away.

Follow us on