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Migraine relief: People who suffer from migraine know how debilitating the pain can be during an attack. It is an excruciating neurological disorder that affects millions of people worldwide, across age groups. Migraine pain is said to be caused by abnormal brain activity, inflammation, and blood vessel dilation that can trigger the release of 'pain-causing chemicals', leading to intense, throbbing headaches, which are often accompanied by sensitivity to light and sound. So many people suffer in silence, grappling with the unpredictable and agonising nature of migraine. While traditional treatments have often fallen short of providing complete relief, it has led to a growing interest in exploring cutting-edge therapies like 'cell therapy'. In recent years, significant strides have been made in the realm of regenerative medicine, offering a ray of hope for those seeking effective and long-lasting relief from migraine attacks, says Dr Pradeep Mahajan, regenerative medicine researcher and founder of StemRx Hospital and Research Centre.
According to Dr Mahajan, migraines are complex, recurring neurological episodes that impact approximately 14 per cent of the global population. Unlike ordinary headaches, migraines are influenced by a mix of genetic, environmental, and neurovascular factors, making their root causes difficult to pinpoint. "Despite their prevalence, the lack of a definitive cure continues to drive research into innovative therapies that go beyond symptom management," the doctor states.
The expert says regenerative medicine -- particularly cell therapy -- is now being explored as a novel method to combat the debilitating effects of migraines. "Mesenchymal stem cells (MSCs), known for their anti-inflammatory and immunomodulatory properties, are at the forefront of this research. Derived from a patient's own bone marrow or blood, these cells are processed and prepared for targeted administration to address migraine triggers."
Upon administration, MSCs 'migrate' to inflamed areas, including brain blood vessels implicated in migraines. Dr Mahajan explains that they facilitate tissue repair, reduce the release of pro-inflammatory substances, and help interrupt the chain of events that lead to migraine attacks. Additionally, cell therapy enhances neuroprotection, safeguarding against the neurological damage caused by severe and frequent episodes.
"By stimulating the production of growth factors, this therapy aids in the regeneration of damaged nerves and blood vessels, addressing migraines at their root cause," he adds.
The expert says that research on cell therapy for migraines has yielded promising outcomes. "Patients undergoing this treatment have reported significant reductions in the frequency, intensity, and duration of their attacks, alongside an overall improvement in their quality of life. These findings offer hope that cell therapy could become a transformative solution for migraine sufferers in the future," he concludes.