All about the types of stones in GI tract, preventive measures and treatment options

Here's everything you need to know about gallstones, kidney stones and salivary gland stones.

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Written By: Mita Majumdar | Published : February 24, 2016 4:04 PM IST

All you need to know about gallstones, kidney stones and other stones in GI tract

The first time it was a sort of stabbing pain in the upper abdomen. Gas! I didn t pay much attention to it. The next episode was about a fortnight later, about half-an-hour after a sumptuous fatty meal with friends I met after a year. This time the pain was stronger and lasted for an hour or so. Gradually the pain level and frequency increased and I noticed that the pain was radiating towards the back, right below the shoulder blades. I felt a little relief after vomiting. After enduring the pain for a couple more months, I decided it was time to visit the doctor. I was asked to get an ultrasound scan done. The scan revealed a gallstone, more than a centimetre thick, stuck to the gallbladder wall and partially blocking the bile duct. Doctors recommended the gall bladder be removed surgically.

Why do gallstones form?

The liver produces bile, a fluid which consists of cholesterol, bile salts, and bilirubin. Bile helps the body digest fats and fat-soluble vitamins such as A, D, E, and K. Gallstones may form when there is too much cholesterol, too much bilirubin, or not enough bile salts in the bile, that is, gallstones are formed when there is an imbalance of these substances in the bile.

Gallstones can be yellow-green stones in case of too much cholesterol which has hardened, or it can be a dark coloured pigment stone because of bilirubin imbalance.

Symptoms

In many cases you may not even know that you have gallstones since they do not produce any symptoms and you need not even go for treatment. However, when the gallstones are too large or block the bile ducts, you may experience symptoms of pain which

  • Typically begin to the right of the upper abdomen
  • The pain progresses to the back
  • Pains usually occur in the evening or night
  • Duration is of an hour or more, and never less than half an hour

You may also have the urge to walk around when you are having the pain. Norway researchers found that 71 percent of subjects they studied had the urge of walking. They also found that symptoms of functional indigestion (gastroesophageal reflux, dyspepsia or irritable bowel symptoms) occurred in the vast majority in association with attacks. [1]

Preventive measures

It is difficult to prevent gallstones but you can reduce the risk by

  • Controlling your weight
  • Avoiding high cholesterol foods and choosing low-fat alternatives
  • Staying away from carbs
  • Exercising regularly

Surgical options

The most common surgical procedure for removal of gallbladder is called laparoscopic cholecystectomy. It is performed under anaesthesia. The surgeon will make three or four incisions of 5 mm to 10 mm length, remove the gallbladder along with gallstone, and suture the incisions. The whole procedure will take less than an hour. You may be allowed to go home the morning after surgery if not on the same day. You can resume working within one to two weeks of surgery.

Kidney stones

Kidney stones, just like gallstones, happen because of an unwanted phase in which the dissolved salts in the kidney solidify into crystals.

Why do kidney stones form?

Kidney stone or stones in the lower urinary tract may occur because the patient has low urinary output, is excreting too much salt, or has very acid urine.

Approximately 80% of stones are composed of calcium oxalate and calcium phosphate; 10% of struvite (magnesium ammonium phosphate produced during infection with bacteria that possess the enzyme urease), 9% of uric acid; and the remaining 1% are composed of cystine or ammonium acid urate or are diagnosed as drug-related stones. [2]

Symptoms

Kidney stones can pass on their own without causing any symptoms or needing any treatment. Stones less than 5 mm in diameter have a high chance of passage; those of 5 7 mm have a half chance of passage, and those greater than 7 mm will always require medical intervention. [2]

You may experience symptoms when the kidney stone gets stuck somewhere during the passage in the kidney itself or in the urinary tract (ureter, bladder, or urethra). Symptoms include

  • Pain that begins as a mild discomfort and progresses to extreme severity and plateaus lasting half an hour to more than an hour.
  • Blood in the urine.
  • Pain comes in waves and fluctuates in intensity.
  • If the stone obstructs the ureter region, pain localizes to the flank; as the stone moves down the ureter, pain moves downwards and in front.
  • Pain on urination
  • Pink, red or brown urine; cloudy or foul smelling urine; persistent need to urinate, either urinating more often than usual or urinating in small amount.
  • Nausea and vomiting
  • Fever if there is infection.

Preventive measures

Diet, medical conditions such as obesity, gout, and diabetes, family history of kidney stones, and certain medications are the main risk factors for kidney stone.

Keep a tab on these factors (except of course if it runs in your family) to avoid getting kidney stones. Reduce weight if you are overweight or obese. Take control of your medical conditions. Well, certain medications too can cause kidney stones. Some examples [3]are

  • Allopurinol (Zyloprim)
  • Overuse of laxatives
  • Herbal products used as stimulants and appetite suppressants
  • Potassium channel blockers
  • Potassium-sparing diuretics
  • HAART (highly active antiretroviral therapy)
  • Various therapies for type 2 diabetes
  • Talk to your doctors if you are taking these medicines.

Diet is actually the most important factor for preventing kidney stones. Here s what experts [4] recommend

  • Drink plenty of water. Aim for 2 litres per day of water.
  • Take calcium appropriate for your age. For example, if you are a man aged 50 years to 70 years your calcium intake needs to be 1000 mg/day and 1200 mg/ day for women aged 50 to 70 years. Take 800 to 1000 IU of vitamin D to help absorb the calcium.
  • Limit your intake of sodium to 1500 mg/day
  • Avoid consuming too much of red meats, poultry, and sea food. They tend to increase the uric acid level in the body and aid stone formation.
  • Avoid foods such as spinach, beet root, chocolate, nuts, and cola as they contribute to kidney stone formation.

Surgical options

There are a number of surgical options for kidney stone removal.

Shock wave lithotripsy (SWL) is a safe and minimally invasive procedure that uses high frequency sound waves to break a kidney stone into small pieces, and allow it to pass through the urinary tract.You will be instructed not to drink or eat anything for at least 12 hours before the procedure.

The procedure takes about an hour. You will be given local anaesthesia or, if required, general anaesthesia. The following methods are used

  • You will lie down on a soft cushion through which high frequency sound waves will be transmitted to the kidney. About 2 to 8 thousand shock waves are needed to crush and fragment the stone.
  • You will lie down on a special tub filled with warm water. X-rays are used during the procedure to precisely locate the stone in the kidney, and shock waves to crush the stone will be sent from the machine called Lithotripter. This procedure is called Extracorporeal Shock Wave Lithotripsy or ECSWL.

The Intracorporeal Shock Wave Lithotripsy, also called Laser Lithotripsy technique is used in case of stones in the lower part of the urinary tract, such as ureter or bladder. An endoscope or cystoscopeis used to get close to the stone inside your urinary tract and laser waves are applied to fragment the stone into small particles. The fragments are extracted out or they are passed out naturally during urination.

Percutaneous Nephrolithotomy(PCNL) is a procedure for removing medium sized or large kidney stones, ones which cannot be removed through SWL. Here a nephroscope is passed into the kidney through a track created through the skin at the back. The stone is then crushed to fine particles and passed out through urinary tract.

You ll need to stay in the hospital for 3-4 days.

Open surgery is the most invasive form of treatment for removing kidney stones and is not usually preferred unless

The stone is very large or extremely hard

  • You are extremely obese
  • You have an abnormal kidney
  • You have an infected or non-functional kidney that needs to be removed
  • You may be hospitalized for a week and further it might take 6 weeks to recover at home.

Salivary gland stones

Saliva made by the salivary glands contains enzymes that breakdown starch and fat from the food you ingest. Three pairs of salivary glands are involved in the making of saliva

  • Submandibular glands, under the floor of your mouth; drain saliva up into the floor of your mouth.
  • Parotid glands below and in front of your ears; passes saliva into the inside of your cheeks.
  • Sublingual glands lie just beneath your tongue.

The main chemicals in the saliva are the calcium salts, especially calcium carbonates and phosphates. The size of the stones range from 0.1 to 30 mm, but commonly the submandibular stones are 1.5 to 9 mm in size, and the number of stones range from 1 to 5.

Why do salivary gland stones form?

More than 80 percent of cases are stones in the submandibular glands. This is because it produces a particularly viscous, mucous and more alkaline saliva, with a relatively high concentration of hydroxyapatites and phosphates. This causes saturation of salts, especially when water intake is low and subsequent formation of stones. Moreover, the opening of the main salivary duct of the submandibular gland (Wharton s duct) is narrower than the diameter of the whole duct, so when the saliva ascends towards its opening it tends to get stuck at the opening and calcifies. [5]

Other possible causes are

  • Infection
  • Debris, bacteria or substances migrating in the salivary ducts from oral cavity [6]

Symptoms

The stone blocks the mouth of the duct and the most common symptom is pain and swelling of the affected gland at mealtimes or soon after the meals. The pain is sudden and intense right after you begin eating followed by swelling. The pain and swelling persist for about one to two hours after the meal.

Sometimes, the stone is just lodged in the gland and may not (or maybe, partially) block the duct. Then you experience a dull pain from time to time over the affected gland.

Preventive measures

Drink plenty of fluids, keep your mouth hydrated.

Surgical options

Sialendoscopyis the most used surgical option. Your doctor will first inject a local anaesthesia into the affected duct, then push an endoscope into the affected duct and pull out the stone.

Shock wave lithotripsy is done in cases of large stones. The ultrasound waves break up the stone and the fragments are allowed to pass into the duct. However, it is not very common. Doctors now do the SWL just to break up the large stone and then use sialendoscopy to remove the fragments.

Herbal remedies for gallstones

10 simple ways to prevent kidney stones

6 foods to avoid if you are suffering from kidney stones

5 early symptoms of kidney stones you should know

References

  1. Berhane, T, et al. Pain attacks in non-complicated and complicated gallstone disease have a characteristic pattern and are accompanied by dyspepsia in most patients: The results of a prospective study. Scandinavian Journal of Gastroenterology. Volume 41, Issue 1, 2006, pp 93-101.
  1. Coe FL, Evan A, Worcester E. Kidney stone disease. Journal of Clinical Investigation. 2005;115(10):2598-2608. doi:10.1172/JCI26662.
  1. Kohlstadt L. Treatment and Prevention of Kidney Stones: An Update - American Family Physician. Aafporg. 2016.
  1. Pendick D. 5 steps for preventing kidney stones. Harvard Health Publications, Harvard Medical School. 2013.
  1. Rzymska-Grala I, Stopa Z, Grala B, et al. Salivary gland calculi contemporary methods of imaging. Polish Journal of Radiology. 2010;75(3):25-37.
  2. Singhal A, Singhal P, Ram R, Gupta R. Self-exfoliation of large submandibular stone-report of two cases. Contemporary Clinical Dentistry. 2012;3(Suppl 2):S185-S187. doi:10.4103/0976-237X.101087.

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